Multifunctional peptide-assembled micelles for simultaneously reducing amyloid-? and reactive oxygen species
نویسندگان
چکیده
Multifunctional micelles based on a peptide–polymer for simultaneously targeting A? degradation and ROS scavenging AD therapy.
منابع مشابه
O 22: Reactive Oxygen Species and Epilepsy
Seizure activity has been proposed to result in the generation of reactive oxygen species (ROS), which then contribute to seizure-induced neuronal damage and eventually cell death. Although the mechanisms of seizure-induced ROS generation are unclear, mitochondria and cellular calcium overload have been proposed to have a crucial role. We aim to determine the sources of seizure-induced ROS and ...
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BACKGROUND The object of this study was to develop a thermally and reactive oxygen species-responsive nanocarrier system for cancer therapy. RESULTS PPS-PNIPAm block copolymer was designed and synthesised using a combination of living anionic ring-opening polymerization and atom transfer radical polymerization. The synthesized polymer formed micellar aggregates in water and demonstrated dual ...
متن کاملo 22: reactive oxygen species and epilepsy
seizure activity has been proposed to result in the generation of reactive oxygen species (ros), which then contribute to seizure-induced neuronal damage and eventually cell death. although the mechanisms of seizure-induced ros generation are unclear, mitochondria and cellular calcium overload have been proposed to have a crucial role. we aim to determine the sources of seizure-induced ros and ...
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ژورنال
عنوان ژورنال: Chemical Science
سال: 2021
ISSN: ['2041-6520', '2041-6539']
DOI: https://doi.org/10.1039/d1sc00153a